"Let's Cut to the Chase-I Need a Pill."

Sharpening Host Defenses during Infection: Proteases Cut to the Chase*

The human immune system consists of an intricate network of tightly controlled pathways, where proteases are essential instigators and executioners at multiple levels. Invading microbial pathogens also encode proteases that have evolved to manipulate and dysregulate host proteins, including host proteases during the course of disease. The identification of pathogen proteases as well as their su...

Cut to the chase: quickly achieving high coverage male circumcision.

Metabolomics cuts to the chase to chase the cuts.

type II diabetes5. However, like most proteases, a complete picture of the targets of DPP4 is lacking, which makes it difficult to anticipate metabolic function has prompted the development of a number of small-molecule inhibitors of DPP4, including sitagliptin (Januvia), which was recently approved by the US Food Proteases are enzymes that perform the basic task of cutting up other proteins an...

Caspases as therapeutic targets in Alzheimer's disease: is it time to "cut" to the chase?

Mounting evidence suggests the involvement of caspases in the disease process associated with Alzheimer's disease (AD). The activation of caspases may be responsible for the neurodegeneration associated with AD and several recent studies have suggested that caspases may also play a role in promoting pathogenic mechanisms underlying this disease. Thus, caspase activation and cleavage of the amyl...

from linguistics to literature: a linguistic approach to the study of linguistic deviations in the turkish divan of shahriar

chapter i provides an overview of structural linguistics and touches upon the saussurean dichotomies with the final goal of exploring their relevance to the stylistic studies of literature. to provide evidence for the singificance of the study, chapter ii deals with the controversial issue of linguistics and literature, and presents opposing views which, at the same time, have been central to t...